p97 inhibitor / A potent, selective and reversible inhibitor of the AAA-ATPase p97 (ATPase associated with diverse cellular activities). Ki=3.2 uM. It blocks ubiquitin-dependent protein clearance pathways. Cell permeable.
Product Type:
Biochemicals & reagents
CAS Number:
177355-84-9
Reference:
1) Chou et al. (2011), Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways; Proc. Natl. Acad. Sci. USA, 108 4834
Storage Temperature:
-20°C
Additional Information:
TARGET: ATPase -- PATHWAY: Degradation -- RESEARCH AREA: Ubiquitin/Proteasome