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Agitoxin-2

Agitoxin-2
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Size: 0.5 mg
$583.00
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Catalogue number:
13AGI002-00500
Name:
Agitoxin-2
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Agitoxin-2 is a potent and selective blocker of the Shaker type voltage-gated Kv1.3 and Kv1.1 channels. Agitoxin-2 inhibits Kv1.3 with an IC50 value of around 200 pM and Kv1.1 with an IC50 value of around 140 pM. This peptide toxin was originally isolated from the venom of the Israeli scorpion L. quinquestriatus hebraeus.

Product Type:
Peptides & proteins
CAS Number:
168147-41-9
Storage Temp:
RT
Molecular Weight:
4090.89 Da
Reference:
Anangi R., et al. (2012) Recombinant Expression of Margatoxin and Agitoxin-2 in Pichia pastoris: An Efficient Method for production of KV1.3 Channel Blockers. PLoS ONE; Garcia, M.L. et al. (1994) Purification and characterization of three inhibitors of voltage-dependent K+ channels from Leiurus quinquestriatus var. hebraeus venom. Biochemistry