ClariCELL™ EphB3 Assay Kit

ClariCELL™ kinase phosphorylation cell-based assay kit for EphB3. ClariCELL™ kinase assays test for small molecule-mediated modulatory activity of specific kinases in a human cell background. Cell-based compound potency measurements are important components of the drug discovery process since biochemical potency values often do not translate to cellular activity for a number of reasons including compound membrane permeability, cellular ATP concentration and compound localization. Kit components include: 1) HEK293 cells transiently expressing the full length human kinase, 2) capture antibody, 3) detection antibody, 4) cell lysis buffer, 5) protocols and performance documentation.