Transporter Compounds
Inhibitors and modulators are available for a wide range of transporter targets.
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Transporter Categories
ATP-binding Cassette Family
Gliclazide (SUR1 antagonist) |
ATPases (F-type and V-type)
Abamectin (GABA antagonist, F0F1-ATPase and adenine nucleotide translocator inhibitor) Citreoviridin A (F1F0 ATP synthase inhibitor) Enterostatin (F1-ATPase inhibitor) Nerolidol, synthetic (AChE inhibitor, F0F1-ATP synthase modulator) Oligomycin A (F1F0 ATP synthase inhibitor) Oligomycin B (F1F0 ATP synthase inhibitor) Tentoxin (CF1 ATPase inhibitor) |
ATPases (P-type)
2,5-Di-tert-butyl-4-hydroxyanisole (potential Ca2+ ATPase inhibitor) Bisacodyl (Na+/K+ ATPase inhibitor) Canrenone (Na+/K+ ATPase partial agonist, aldosterone and AR antagonist) Cetrimide (H+ ATP synthase inhibitor) Chelerythrine Chloride (PKC and Na+/K+ ATPase inhibitor) Clotrimazole (14-α demethylase, H+/K+ ATPase, Na+/K+ ATPase inhibitor) Cyclopiazonic Acid (SERCA inhibitor) Doxepin Hydrochloride (FIASMA, 5-HT1/2, M1-5 mAChR, α1-adrenergic, histamine H1/2 antagonist, SERT, NET, H+/K+ ATPase inhibitor) Esomeprazole Magnesium Trihydrate (H+/K+ ATPase inhibitor) Esomeprazole Potassium (H+/K+ ATPase and MAO-A/B inhibitor) Gastrin I (CCK2 agonist, indirect H+/K+ ATPase activator) Isoflurane (Ca2+ ATPase and ATP-sensitive K+ channel activator, GABA-A and GlyR potentiator, NMDA antagonist, L-type Ca2+, delayed rectifier K+, A-type K+ channel blocker) Lansoprazole (H+/K+ ATPase inhibitor) Lopinavir (HIV protease inhibitor, SERCA inhibitor) Oligomycin (oxidative phosphorylation inhibitor, potential Na+/K+ ATPase inhibitor) Omeprazole (H+/K+ ATPase inhibitor) Pantoprazole (H+/K+ ATPase and ROCK-2 inhibitor) Pantoprazole Sodium Sesquihydrate (H+/K+ ATPase and ROCK-2 inhibitor) Paxilline (BK K+ channel inhibitor, SERCA inhibitor) Perillyl Alcohol (farnesyl transferase, geranylgeranyl transferase, telomerase, Na+/K+ ATPase inhibitor) Protodioscin (Na+/K+ ATPase and Ca2+/Mg2+ ATPase activator) Rabeprazole Sodium (H+/K+ ATPase and Scpc phosphatase inhibitor) Tenatoprazole (H+/K+ ATPase inhibitor) Thapsigargin (SERCA inhibitor) Urodilatin CCC (Na+/K+ ATPase inhibitor) Vindoline (Kv2.1 K+ channel blocker and H+/K+ ATPase inhibitor) |
Major Facilitator Superfamily (MFS)
Levetiracetam (SV2A synaptic vesicle inhibitor) |
SLC Superfamily of Solute Carriers
Amantadine Hydrochloride (Viral M2 proton channel blocker, MAO-A, NET, NMDA, α7 nAChR antagonist) Amantadine Sulfate (Viral M2 proton channel blocker, MAO-A, NET, NMDA, α7 nAChR antagonist) Amitriptyline Hydrochloride (FIASMA, σ1, RyR2, TrkA/B agonist, 5-HT2/6/7, M1-5 mAChR, histamine H1/4, α1-adr. antagonist, SERT, NET inhibitor, Kv1.1/7.2/7.3 K+, L-type Ca2+ channel blocker) Amoxapine (5-HT2/3/6/7, D2/3/4, histamine H1, α1-adrenergic antagonist, SERT and NET inhibitor, hERG K+ channel blocker) Aripiprazole (D2 and 5-HT1A partial agonist, 5-HT2C/6/7 antagonist, SERT inhibitor) Atomoxetine Hydrochloride (NET and SERT inhibitor, NMDA antagonist) Benztropine Mesylate (DAT inhibitor) Brompheniramine Maleate (histamine H1 and mAChR antagonist, potential SERT and MAO-B inhibitor) Bumetanide (NKCC symporter and KCC2 co-transporter inhibitor, potential GABA-A antagonist) Chlorpheniramine Maleate (histamine H1 antagonist, SERT and NET inhibitor) Citalopram Hydrobromide (SERT inhibitor) Clomipramine Hydrochloride (FIASMA, mAChR, 5-HT2/3/6/7, α1/2-adrenergic antagonist, SERT and NET inhibitor, hERG K+ and L-type Ca2+ channel blocker) Dapoxetine Hydrochloride (SERT inhibitor, potential voltage-gated K+ channel blocker) Desvenlafaxine Succinate (SERT and NET inhibitor) Dextromethorphan Hydrobromide Hydrate (σ1/2and μ/κ/δ-OR agonist, α3β4/α4β2/α7 nAChR, SERT, NET, NMDA antagonist) Dihydrokainic Acid (NMDA agonist, GLT-1 inhibitor) Doxepin Hydrochloride (FIASMA, 5-HT1/2, M1-5 mAChR, α1-adrenergic, histamine H1/2 antagonist, SERT, NET, H+/K+ ATPase inhibitor) Duloxetine Hydrochloride (SERT and NET inhibitor, Nav1.7 Na+ channel blocker) Escitalopram Oxalate (SERT inhibitor) Fluoxetine Hydrochloride (FIASMA, SERT inhibitor, 5-HT and σ1 antagonist) Fluvoxamine Maleate (FIASMA, 5-HT3 and σ1 agonist, SERT inhibitor) Furosemide (NKCC symporter inhibitor, CFTR Cl- channel blocker, GABA-A antagonist) Hydrochlorothiazide (NCCT inhibitor, carbonic anhydrase I inhibitor) Indinavir Sulfate (HIV protease, GLUT4, calpain inhibitor) Luteolin (DAT and NET potentiator, HSP90, IGF-1R, PDE inhibitor, potential α2-adrenergic antagonist) Maprotiline Hydrochloride (FIASMA, histamine H1, 5-HT2, mAChR, α1-adrenergic antagonist, L-type Ca2+ channel blocker, NET inhibitor) Nefazodone Hydrochloride (5-HT2 antagonist, SERT and NET inhibitor, hERG K+ channel blocker) Paroxetine Hydrochloride Hemihydrate (FIASMA, SERT and NET inhibitor, mAChR antagonist) Riluzole (TRPC5 agonist, PTR1 inhibitor, voltage-gated Na+ channel blocker, GLT-1 modulator) Sertraline Hydrochloride (FIASMA, SERT and DAT inhibitor, α1-adrenergic antagonist, potential σ1 antagonist) D-Tetrahydropalmatine (D1 antagonist, organic cation transporter 1 inhibitor) Thioridazine Hydrochloride (FIASMA, D1-5, histamine H1/2, M1-5 mAChR, 5-HT1/2/5/6/7, α1/2-adrenergic antagonist, NET inhibitor, hERG K+ channel inhibitor) Torsemide (NKCC symporter and HSP90 inhibitor) Trazodone Hydrochloride (5-HT1A partial agonist, 5-HT2, histamine, α1/2-adrenergic antagonist, SERT inhibitor, voltage-gated K+ channel blocker) Triacsin C (Acyl-CoA synthetase inhibitor) Venlafaxine Hydrochloride (SERT, NET, MAO inhibitor) Vilazodone (5-HT1A partial agonist, SERT inhibitor) Vortioxetine (5-HT1A agonist, 5-HT1B partial agonist, 5-HT3A/7 antagonist, SERT inhibitor, potential β1-adrenergic agonist) |

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