PODS™ - Slow Release Growth Factors

Mayflower Bioscience is pleased to be introducing PODS™ Growth Factors, a revolution in growth factor quality, stability and bioavailability. We expect this technology to have a signficant impact on a wide range of cell biology and tissue engineering applications.

Developed by Cell Guidance Systems, PODS™ proteins are made using an insect cell expression system in which the active protein is co-expressed alongside polyhedrin carrier protein. Polyhedrin forms microcrystals within insect cells which specifically capture the active protein to form a co-crystal complex. The active protein is captured in its nascent, natively folded form with limited scope for proteolytic degradation. Consequently, excellent levels of bioactivity are observed. The PODS™ co-crystals provide a sustained release mechanism and can be used to functionalize surfaces.From Activin to Wnt3a - more than 20 different growth factors are now available in this novel format.

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