Recombinant adenoviruses possess the tropism of the parent viruses, which can infect all cells possessing the appropriate primary adenovirus receptor CAR (Coxsackie Adenovirus Receptor). However, some cell types express only low levels or even no CAR, making efficient recombinant adenovirus transduction almost impossible.
AdenoBOOST specifically bridges the adenovirus surface to the cell membrane, thereby enhancing gene expression by 20 to 50-fold into cell types which lack the primary adenovirus receptor CAR.
AdenoBOOST is a non-toxic peptide-based solution simply added to the adenovirus prior to transduction. It specifically forms a bridge from the adenovirus surface to the cell membrane increasing the binding of adenovirus to the cell surface.
- 20 to 50-fold enhanced expression
- Access to nearly all cell types
- Use less adenovirus
- No cell toxicity
Note: product availability depends on country - see product detail page.
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|AdenoBOOST™ Adenovirus Transduction Enhancer Solution SB-P-AV-101-01 · SIRION Biotech||