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G-CSF, mouse recombinant

Catalogue number:
GFM14-100
Size:
100 µg
Product is available in:
  • USA
  • Canada
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G-CSF is a glycoprotein containing internal disulfide bonds. It induces the survival, proliferation, and differentiation of neutrophilic granulocyte precursor cells and functionally activates mature blood neutrophils. Among the family of colony-stimulating factors, G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines. The synthesis of G-CSF can be induced by bacterial endotoxins, TNF, IL-1 and GM-CSF. Prostaglandin E2 inhibits the synthesis of G-CSF. In epithelial, endothelial, and fibroblastic cells secretion of G-CSF is induced by IL-17. Recombinant Mouse G-CSF is a single, non- glycosylated, polypeptide chain.

Product Type:

Peptides & proteins

Alternative Names:

CSF-3, MGI-1G, GM-CSFβ, pluripoietin

Storage Temperature:

-20°C

Additional Information:

NAME: Granulocyte Colony Stimulating Factor; ACCESSION/UNIPROT#: P09920; EXPRESSION SYSTEM: E.coli; FORMAT: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium citrate, pH 3.0. Reconstitute in sterile water at 0.1 mg/mL.; TESTING: NFS-60 cell proliferation with an acceptance criteria of 50 pg/mL (ED50), 2 x 10^7 units/mg.; #AA: 179; SEQUENCE: MVPLVTVSAL PPSLPLPRSF LLKSLEQVRK IQASGSVLLE QLCATYKLCH PEELVLLGHS LGIPKASLSG CSSQALQQTQ CLSQLHSGLC LYQGLLQALS GISPALAPTL DLLQLDVANF ATTIWQQMEN LGVAPTVQPT QSAMPAFTSA FQRRAGGVLA ISYLQGFLET ARLALHHLA

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