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G-CSF (animal free), human recombinant

Catalogue number:
GFH72AF-500
Size:
500 µg
Product is available in:
  • USA
  • Canada
$2895.00 Shipping is calculated in checkout

Human G-CSF induces the survival, proliferation and differentiation of neutrophilic granulocyte precursor cells and functionally activates mature blood neutrophils. Among the family of colony-stimulating factors, G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines. The synthesis of G-CSF can be induced by bacterial endotoxins, TNF, IL-1 and GM-CSF. Prostaglandin E2 inhibits the synthesis of G-CSF. In epithelial, endothelial and fibroblastic cells secretion of G-CSF is induced by IL-17. Human and mouse G-CSF are cross-reactive. Recombinant Human G-CSF is a single, non-glycosylated polypeptide chain.

Product Type:

Peptides & proteins

Alternative Names:

CSF-3, MGI-1G, GM-CSFβ, pluripoietin

Storage Temperature:

-20°C

Additional Information:

Produced using animal free raw components and processes, in a non-mammalian system. Ideal for researchers concerned about the risks and effects of contaminating viruses, prions and trace growth factors from FBS and animal-derived ingredients used in standard recombinant protein production techniques. Endotoxin levels are less than 1.0 EU per ug protein via LAL. Bioactivity is comparable to recombinant protein produced in traditional techniques.